Vanderbilt University School of Medicine (2025)

Cumberbatch D, Mori T, Yang J, Mi D, Vinson P, Weaver CD, Johnson CH. A BRET Ca2+ sensor enables high-throughput screening in the presence of background fluorescence.

Sci Signal [print-electronic]

. 2022 Aug 8/16/2022; 15(747): eabq7618. PMID: 35973028, DOI: 10.1126/scisignal.abq7618, ISSN: 1937-9145.

Kelly KP, Borsetti H, Wenzler ME, Ustione A, Kim K, Christov PP, Ramirez B, Bauer JA, Piston DW, Johnson CH, Sulikowski GA. Screen for Small-Molecule Modulators of Circadian Rhythms Reveals Phenazine as a Redox-State Modifying Clockwork Tuner.

ACS Chem Biol [print-electronic]

. 2022 Jul 7/15/2022; 17(7): 1658-64. PMID: 35679588, PMCID: PMC9398883, DOI: 10.1021/acschembio.2c00240, ISSN: 1554-8937.

Shi SQ, Mahoney CE, Houdek P, Zhao W, Anderson MP, Zhuo X, Beaudet A, Sumova A, Scammell TE, Johnson CH. Circadian Rhythms and Sleep Are Dependent Upon Expression Levels of Key Ubiquitin Ligase Ube3a.

Front Behav Neurosci

. 2022; 16: 837523. PMID: 35401134, PMCID: PMC8989470, DOI: 10.3389/fnbeh.2022.837523, ISSN: 1662-5153.

Ellis BM, Babele PK, May JC, Johnson CH, Pfleger BF, Young JD, McLean JA. Accelerating strain phenotyping with desorption electrospray ionization-imaging mass spectrometry and untargeted analysis of intact microbial colonies.

Proc Natl Acad Sci U S A

. 2021 Dec 12/7/2021; 118(49): PMID: 34857637, PMCID: PMC8670462, PII: 2109633118, DOI: 10.1073/pnas.2109633118, ISSN: 1091-6490.

Kelly KP, Ellacott KLJ, Chen H, McGuinness OP, Johnson CH. Time-optimized feeding is beneficial without enforced fasting.

Open Biol [print-electronic]

. 2021 Oct; 11(10): 210183. PMID: 34610264, PMCID: PMC8492177, DOI: 10.1098/rsob.210183, ISSN: 2046-2441.

Amaral DT, Johnson CH, Viviani VR. RNA-Seq analysis of the blue light-emitting Orfelia fultoni (Diptera: Keroplatidae) suggest photoecological adaptations at the molecular level.

Comp Biochem Physiol Part D Genomics Proteomics [print-electronic]

. 2021 Sep; 39: 100840. PMID: 34022525, PMCID: PMC8495875, PII: S1744-117X(21)00052-6, DOI: 10.1016/j.cbd.2021.100840, ISSN: 1878-0407.

Wang B, Xu Y, Wang X, Yuan JS, Johnson CH, Young JD, Yu J. A guanidine-degrading enzyme controls genomic stability of ethylene-producing cyanobacteria.

Nat Commun

. 2021 Aug 8/26/2021; 12(1): 5150. PMID: 34446715, PMCID: PMC8390497, PII: 10.1038/s41467-021-25369-x, DOI: 10.1038/s41467-021-25369-x, ISSN: 2041-1723.

Ralph MR, Shi SQ, Johnson CH, Houdek P, Shrestha TC, Crosby P, O'Neill JS, Sládek M, Stinchcombe AR, Sumová A. Targeted modification of the Per2 clock gene alters circadian function in mPer2luciferase (mPer2Luc) mice.

PLoS Comput Biol

. 2021 May; 17(5): e1008987. PMID: 34048425, PMCID: PMC8191895, PII: PCOMPBIOL-D-20-01559, DOI: 10.1371/journal.pcbi.1008987, ISSN: 1553-7358.

Yang J, Johnson CH. Bioluminescent Sensors for Ca++ Flux Imaging and the Introduction of a New Intensity-Based Ca++ Sensor.

Front Bioeng Biotechnol

. 2021; 9: 773353. PMID: 34778237, PMCID: PMC8578923, PII: 773353, DOI: 10.3389/fbioe.2021.773353, ISSN: 2296-4185.

Jabbur ML, Johnson CH. Spectres of Clock Evolution: Past, Present, and Yet to Come.

Front Physiol

. 2021; 12: 815847. PMID: 35222066, PMCID: PMC8874327, DOI: 10.3389/fphys.2021.815847, ISSN: 1664-042X.

Davis CR, Johnson CH, Robertson JB. A bioluminescent reporter for the halophilic archaeon Haloferax volcanii.

Extremophiles [print-electronic]

. 2020 Sep; 24(5): 773-85. PMID: 32749548, PMCID: PMC7462420, PII: 10.1007/s00792-020-01193-x, DOI: 10.1007/s00792-020-01193-x, ISSN: 1433-4909.

Davis CR, Johnson CH, Robertson JB. A bioluminescent reporter for the halophilic archaeon Haloferax volcanii.

Extremophiles [print-electronic]

. 2020 Sep; 24(5): 773-85. PMID: 32749548, PMCID: PMC7462420, PII: 10.1007/s00792-020-01193-x, DOI: 10.1007/s00792-020-01193-x, ISSN: 1433-4909.

Cheah YE, Xu Y, Sacco SA, Babele PK, Zheng AO, Johnson CH, Young JD. Systematic identification and elimination of flux bottlenecks in the aldehyde production pathway of Synechococcus elongatus PCC 7942.

Metab Eng [print-electronic]

. 2020 Jul; 60: 56-65. PMID: 32222320, PMCID: PMC7217728, PII: S1096-7176(20)30062-8, DOI: 10.1016/j.ymben.2020.03.007, ISSN: 1096-7184.

Cheah YE, Xu Y, Sacco SA, Babele PK, Zheng AO, Johnson CH, Young JD. Systematic identification and elimination of flux bottlenecks in the aldehyde production pathway of Synechococcus elongatus PCC 7942.

Metab Eng [print-electronic]

. 2020 Jul; 60: 56-65. PMID: 32222320, PMCID: PMC7217728, PII: S1096-7176(20)30062-8, DOI: 10.1016/j.ymben.2020.03.007, ISSN: 1096-7184.

Viviani VR, Silva JR, Amaral DT, Bevilaqua VR, Abdalla FC, Branchini BR, Johnson CH. A new brilliantly blue-emitting luciferin-luciferase system from Orfelia fultoni and Keroplatinae (Diptera).

Sci Rep

. 2020 Jun 6/15/2020; 10(1): 9608. PMID: 32541805, PMCID: PMC7295969, PII: 10.1038/s41598-020-66286-1, DOI: 10.1038/s41598-020-66286-1, ISSN: 2045-2322.

Viviani VR, Silva JR, Amaral DT, Bevilaqua VR, Abdalla FC, Branchini BR, Johnson CH. A new brilliantly blue-emitting luciferin-luciferase system from Orfelia fultoni and Keroplatinae (Diptera).

Sci Rep

. 2020 Jun 6/15/2020; 10(1): 9608. PMID: 32541805, PMCID: PMC7295969, PII: 10.1038/s41598-020-66286-1, DOI: 10.1038/s41598-020-66286-1, ISSN: 2045-2322.

Fustin JM, Ye S, Rakers C, Kaneko K, Fukumoto K, Yamano M, Versteven M, Grünewald E, Cargill SJ, Tamai TK, Xu Y, Jabbur ML, Kojima R, Lamberti ML, Yoshioka-Kobayashi K, Whitmore D, Tammam S, Howell PL, Kageyama R, Matsuo T, Stanewsky R, Golombek DA, Johnson CH, Kakeya H, van Ooijen G, Okamura H. Publisher Correction: Methylation deficiency disrupts biological rhythms from bacteria to humans.

Commun Biol

. 2020 Jun 6/4/2020; 3(1): 295. PMID: 32499511, PMCID: PMC7272646, PII: 10.1038/s42003-020-1031-0, DOI: 10.1038/s42003-020-1031-0, ISSN: 2399-3642.

Kim P, Porr B, Mori T, Kim YS, Johnson CH, Diekman CO, Kim YI. CikA, an Input Pathway Component, Senses the Oxidized Quinone Signal to Generate Phase Delays in the Cyanobacterial Circadian Clock.

J Biol Rhythms [print-electronic]

. 2020 Jun; 35(3): 227-34. PMID: 31983264, PMCID: PMC7269861, DOI: 10.1177/0748730419900868, ISSN: 1552-4531.

Kim P, Porr B, Mori T, Kim YS, Johnson CH, Diekman CO, Kim YI. CikA, an Input Pathway Component, Senses the Oxidized Quinone Signal to Generate Phase Delays in the Cyanobacterial Circadian Clock.

J Biol Rhythms [print-electronic]

. 2020 Jun; 35(3): 227-34. PMID: 31983264, PMCID: PMC7269861, DOI: 10.1177/0748730419900868, ISSN: 1552-4531.

Fustin JM, Ye S, Rakers C, Kaneko K, Fukumoto K, Yamano M, Versteven M, Grünewald E, Cargill SJ, Tamai TK, Xu Y, Jabbur ML, Kojima R, Lamberti ML, Yoshioka-Kobayashi K, Whitmore D, Tammam S, Howell PL, Kageyama R, Matsuo T, Stanewsky R, Golombek DA, Johnson CH, Kakeya H, van Ooijen G, Okamura H. Methylation deficiency disrupts biological rhythms from bacteria to humans.

Commun Biol

. 2020 May 5/6/2020; 3(1): 211. PMID: 32376902, PMCID: PMC7203018, PII: 10.1038/s42003-020-0942-0, DOI: 10.1038/s42003-020-0942-0, ISSN: 2399-3642.

Fustin JM, Ye S, Rakers C, Kaneko K, Fukumoto K, Yamano M, Versteven M, Grünewald E, Cargill SJ, Tamai TK, Xu Y, Jabbur ML, Kojima R, Lamberti ML, Yoshioka-Kobayashi K, Whitmore D, Tammam S, Howell PL, Kageyama R, Matsuo T, Stanewsky R, Golombek DA, Johnson CH, Kakeya H, van Ooijen G, Okamura H. Methylation deficiency disrupts biological rhythms from bacteria to humans.

Commun Biol

. 2020 May 5/6/2020; 3(1): 211. PMID: 32376902, PMCID: PMC7203018, PII: 10.1038/s42003-020-0942-0, DOI: 10.1038/s42003-020-0942-0, ISSN: 2399-3642.

Kelly KP, McGuinness OP, Buchowski M, Hughey JJ, Chen H, Powers J, Page T, Johnson CH. Eating breakfast and avoiding late-evening snacking sustains lipid oxidation.

PLoS Biol

. 2020 Feb; 18(2): e3000622. PMID: 32108181, PMCID: PMC7046182, PII: PBIOLOGY-D-19-03332, DOI: 10.1371/journal.pbio.3000622, ISSN: 1545-7885.

Hellweger FL, Jabbur ML, Johnson CH, van Sebille E, Sasaki H. Circadian clock helps cyanobacteria manage energy in coastal and high latitude ocean.

ISME J [print-electronic]

. 2020 Feb; 14(2): 560-8. PMID: 31685937, PMCID: PMC6976579, PII: 10.1038/s41396-019-0547-0, DOI: 10.1038/s41396-019-0547-0, ISSN: 1751-7370.

Hellweger FL, Jabbur ML, Johnson CH, van Sebille E, Sasaki H. Circadian clock helps cyanobacteria manage energy in coastal and high latitude ocean.

ISME J [print-electronic]

. 2020 Feb; 14(2): 560-8. PMID: 31685937, PMCID: PMC6976579, PII: 10.1038/s41396-019-0547-0, DOI: 10.1038/s41396-019-0547-0, ISSN: 1751-7370.

Kelly KP, McGuinness OP, Buchowski M, Hughey JJ, Chen H, Powers J, Page T, Johnson CH. Eating breakfast and avoiding late-evening snacking sustains lipid oxidation.

PLoS Biol

. 2020 Feb; 18(2): e3000622. PMID: 32108181, PMCID: PMC7046182, PII: PBIOLOGY-D-19-03332, DOI: 10.1371/journal.pbio.3000622, ISSN: 1545-7885.

Guo G, Wang K, Hu SS, Tian T, Liu P, Mori T, Chen P, Johnson CH, Qin X. Autokinase Activity of Casein Kinase 1 d/e Governs the Period of Mammalian Circadian Rhythms.

J Biol Rhythms [print-electronic]

. 2019 Oct; 34(5): 482-96. PMID: 31392916, PMCID: PMC7007343, DOI: 10.1177/0748730419865406, ISSN: 1552-4531.

Guo G, Wang K, Hu SS, Tian T, Liu P, Mori T, Chen P, Johnson CH, Qin X. Autokinase Activity of Casein Kinase 1 d/e Governs the Period of Mammalian Circadian Rhythms.

J Biol Rhythms [print-electronic]

. 2019 Oct; 34(5): 482-96. PMID: 31392916, PMCID: PMC7007343, DOI: 10.1177/0748730419865406, ISSN: 1552-4531.

Shi SQ, Johnson CH. Circadian biology and sleep in monogenic neurological disorders and its potential application in drug discovery.

Curr Opin Behav Sci [print-electronic]

. 2019 Feb; 25: 23-30. PMID: 31289731, PMCID: PMC6615557, DOI: 10.1016/j.cobeha.2018.06.006, ISSN: 2352-1546.

Shi SQ, Johnson CH. Circadian biology and sleep in monogenic neurological disorders and its potential application in drug discovery.

Curr Opin Behav Sci [print-electronic]

. 2019 Feb; 25: 23-30. PMID: 31289731, PMCID: PMC6615557, DOI: 10.1016/j.cobeha.2018.06.006, ISSN: 2352-1546.

Mori T, Sugiyama S, Byrne M, Johnson CH, Uchihashi T, Ando T. Revealing circadian mechanisms of integration and resilience by visualizing clock proteins working in real time.

Nat Commun

. 2018 Aug 8/14/2018; 9(1): 3245. PMID: 30108211, PMCID: PMC6092398, PII: 10.1038/s41467-018-05438-4, DOI: 10.1038/s41467-018-05438-4, ISSN: 2041-1723.

Mori T, Sugiyama S, Byrne M, Johnson CH, Uchihashi T, Ando T. Revealing circadian mechanisms of integration and resilience by visualizing clock proteins working in real time.

Nat Commun

. 2018 Aug 8/14/2018; 9(1): 3245. PMID: 30108211, PMCID: PMC6092398, PII: 10.1038/s41467-018-05438-4, DOI: 10.1038/s41467-018-05438-4, ISSN: 2041-1723.

Hughes ME, Abruzzi KC, Allada R, Anafi R, Arpat AB, Asher G, Baldi P, de Bekker C, Bell-Pedersen D, Blau J, Brown S, Ceriani MF, Chen Z, Chiu JC, Cox J, Crowell AM, DeBruyne JP, Dijk DJ, DiTacchio L, Doyle FJ, Duffield GE, Dunlap JC, Eckel-Mahan K, Esser KA, FitzGerald GA, Forger DB, Francey LJ, Fu YH, Gachon F, Gatfield D, de Goede P, Golden SS, Green C, Harer J, Harmer S, Haspel J, Hastings MH, Herzel H, Herzog ED, Hoffmann C, Hong C, Hughey JJ, Hurley JM, de la Iglesia HO, Johnson C, Kay SA, Koike N, Kornacker K, Kramer A, Lamia K, Leise T, Lewis SA, Li J, Li X, Liu AC, Loros JJ, Martino TA, Menet JS, Merrow M, Millar AJ, Mockler T, Naef F, Nagoshi E, Nitabach MN, Olmedo M, Nusinow DA, Ptácek LJ, Rand D, Reddy AB, Robles MS, Roenneberg T, Rosbash M, Ruben MD, Rund SSC, Sancar A, Sassone-Corsi P, Sehgal A, Sherrill-Mix S, Skene DJ, Storch KF, Takahashi JS, Ueda HR, Wang H, Weitz C, Westermark PO, Wijnen H, Xu Y, Wu G, Yoo SH, Young M, Zhang EE, Zielinski T, Hogenesch JB. Guidelines for Genome-Scale Analysis of Biological Rhythms.

J. Biol. Rhythms [print-electronic]

. 2017 Oct; 32(5): 380-93. PMID: 29098954, PMCID: PMC5692188, DOI: 10.1177/0748730417728663.

Jazmin LJ, Xu Y, Cheah YE, Adebiyi AO, Johnson CH, Young JD. Isotopically nonstationary (13)C flux analysis of cyanobacterial isobutyraldehyde production.

Metab. Eng [print-electronic]

. 2017 Jul; 42: 9-18. PMID: 28479191, PII: S1096-7176(16)30156-2, DOI: 10.1016/j.ymben.2017.05.001, ISSN: 1096-7184.

Tackenberg MC, Johnson CH, Page TL, Daan S. Revealing Oft-cited but Unpublished Papers of Colin Pittendrigh and Coworkers.

J. Biol. Rhythms [print-electronic]

. 2017 Jul 7/1/2017; 748730417716685. PMID: 28766460, DOI: 10.1177/0748730417716685, ISSN: 1552-4531.

Johnson CH, Zhao C, Xu Y, Mori T. Timing the day: what makes bacterial clocks tick?.

Nat. Rev. Microbiol [print-electronic]

. 2017 Apr; 15(4): 232-42. PMID: 28216658, PII: nrmicro.2016.196, DOI: 10.1038/nrmicro.2016.196, ISSN: 1740-1534.

Yang J, Cumberbatch D, Centanni S, Shi SQ, Winder D, Webb D, Johnson CH. Coupling optogenetic stimulation with NanoLuc-based luminescence (BRET) Ca(++) sensing.

Nat Commun

. 2016 Oct 10/27/2016; 7: 13268. PMID: 27786307, PMCID: PMC5476805, PII: ncomms13268, DOI: 10.1038/ncomms13268, ISSN: 2041-1723.

Ma P, Mori T, Zhao C, Thiel T, Johnson CH. Evolution of KaiC-Dependent Timekeepers: A Proto-circadian Timing Mechanism Confers Adaptive Fitness in the Purple Bacterium Rhodopseudomonas palustris.

PLoS Genet

. 2016 Mar; 12(3): e1005922. PMID: 26982486, PMCID: PMC4794148, PII: PGENETICS-D-15-01683, DOI: 10.1371/journal.pgen.1005922, ISSN: 1553-7404.

Shi SQ, White MJ, Borsetti HM, Pendergast JS, Hida A, Ciarleglio CM, de Verteuil PA, Cadar AG, Cala C, McMahon DG, Shelton RC, Williams SM, Johnson CH. Molecular analyses of circadian gene variants reveal sex-dependent links between depression and clocks.

Transl Psychiatry

. 2016; 6: e748. PMID: 26926884, PMCID: PMC4872462, PII: tp20169, DOI: 10.1038/tp.2016.9, ISSN: 2158-3188.

Zhang Y, Robertson JB, Xie Q, Johnson CH. Monitoring Intracellular pH Change with a Genetically Encoded and Ratiometric Luminescence Sensor in Yeast and Mammalian Cells.

Methods Mol. Biol

. 2016; 1461: 117-30. PMID: 27424899, DOI: 10.1007/978-1-4939-3813-1_9, ISSN: 1940-6029.

Mori T, Mchaourab H, Johnson CH. Circadian Clocks: Unexpected Biochemical Cogs.

Curr. Biol

. 2015 Oct 10/5/2015; 25(19): R842-4. PMID: 26439342, PMCID: PMC4697453, PII: S0960-9822(15)00997-5, DOI: 10.1016/j.cub.2015.08.026, ISSN: 1879-0445.

Qin X, Mori T, Zhang Y, Johnson CH. PER2 Differentially Regulates Clock Phosphorylation versus Transcription by Reciprocal Switching of CK1e Activity.

J. Biol. Rhythms

. 2015 Jun; 30(3): 206-16. PMID: 25994100, PMCID: PMC4697459, PII: 30/3/206, DOI: 10.1177/0748730415582127, ISSN: 1552-4531.

Shi SQ, Bichell TJ, Ihrie RA, Johnson CH. Ube3a imprinting impairs circadian robustness in Angelman syndrome models.

Curr. Biol [print-electronic]

. 2015 Mar 3/2/2015; 25(5): 537-45. PMID: 25660546, PMCID: PMC4348236, PII: S0960-9822(14)01650-9, DOI: 10.1016/j.cub.2014.12.047, ISSN: 1879-0445.

Egli M, Johnson CH. Biochemistry that times the day.

Biochemistry [print-electronic]

. 2015 Jan 1/20/2015; 54(2): 104-9. PMID: 25514019, PMCID: PMC4303296, DOI: 10.1021/bi5014968, ISSN: 1520-4995.

Veatch OJ, Pendergast JS, Allen MJ, Leu RM, Johnson CH, Elsea SH, Malow BA. Genetic variation in melatonin pathway enzymes in children with autism spectrum disorder and comorbid sleep onset delay.

J Autism Dev Disord

. 2015 Jan; 45(1): 100-10. PMID: 25059483, PMCID: PMC4289108, DOI: 10.1007/s10803-014-2197-4, ISSN: 1573-3432.

Veatch OJ, Pendergast JS, Allen MJ, Leu RM, Johnson CH, Elsea SH, Malow BA. Genetic variation in melatonin pathway enzymes in children with autism spectrum disorder and comorbid sleep onset delay.

J Autism Dev Disord

. 2015 Jan; 45(1): 100-10. PMID: 25059483, PMCID: PMC4289108, DOI: 10.1007/s10803-014-2197-4, ISSN: 1573-3432.

Greenberg EP, Nealson KH, Johnson CH. Woody Hastings: 65 years of fun.

Proc. Natl. Acad. Sci. U.S.A [print-electronic]

. 2014 Oct 10/21/2014; 111(42): 14964-5. PMID: 25271327, PMCID: PMC4210301, PII: 1415972111, DOI: 10.1073/pnas.1415972111, ISSN: 1091-6490.

Pattanayek R, Xu Y, Lamichhane A, Johnson CH, Egli M. An arginine tetrad as mediator of input-dependent and input-independent ATPases in the clock protein KaiC.

Acta Crystallogr. D Biol. Crystallogr [print-electronic]

. 2014 May; 70(Pt 5): 1375-90. PMID: 24816106, PII: S1399004714003228, DOI: 10.1107/S1399004714003228, ISSN: 1399-0047.

Pattanayek R, Xu Y, Lamichhane A, Johnson CH, Egli M. An arginine tetrad as mediator of input-dependent and input-independent ATPases in the clock protein KaiC.

Acta Crystallogr. D Biol. Crystallogr [print-electronic]

. 2014 May; 70(Pt 5): 1375-90. PMID: 24816106, PMCID: PMC4722857, PII: S1399004714003228, DOI: 10.1107/S1399004714003228, ISSN: 1399-0047.

Yan Y, Jiang L, Aufderheide KJ, Wright GA, Terekhov A, Costa L, Qin K, McCleery WT, Fellenstein JJ, Ustione A, Robertson JB, Johnson CH, Piston DW, Hutson MS, Wikswo JP, Hofmeister W, Janetopoulos C. A microfluidic-enabled mechanical microcompressor for the immobilization of live single- and multi-cellular specimens.

Microsc. Microanal [print-electronic]

. 2014 Feb; 20(1): 141-51. PMID: 24444078, PMCID: PMC4026272, PII: S1431927613014037, DOI: 10.1017/S1431927613014037, ISSN: 1435-8115.

Yan Y, Jiang L, Aufderheide KJ, Wright GA, Terekhov A, Costa L, Qin K, McCleery WT, Fellenstein JJ, Ustione A, Robertson JB, Johnson CH, Piston DW, Hutson MS, Wikswo JP, Hofmeister W, Janetopoulos C. A microfluidic-enabled mechanical microcompressor for the immobilization of live single- and multi-cellular specimens.

Microsc. Microanal [print-electronic]

. 2014 Feb; 20(1): 141-51. PMID: 24444078, PMCID: PMC4026272, PII: S1431927613014037, DOI: 10.1017/S1431927613014037, ISSN: 1435-8115.

Johnson CH, Egli M. Metabolic compensation and circadian resilience in prokaryotic cyanobacteria.

Annu. Rev. Biochem

. 2014; 83: 221-47. PMID: 24905782, PMCID: PMC4259047, DOI: 10.1146/annurev-biochem-060713-035632, ISSN: 1545-4509.

Robertson JB, Davis CR, Johnson CH. Visible light alters yeast metabolic rhythms by inhibiting respiration.

Proc. Natl. Acad. Sci. U.S.A [print-electronic]

. 2013 Dec 12/24/2013; 110(52): 21130-5. PMID: 24297928, PMCID: PMC3876234, PII: 1313369110, DOI: 10.1073/pnas.1313369110, ISSN: 1091-6490.

Xu Y, Weyman PD, Umetani M, Xiong J, Qin X, Xu Q, Iwasaki H, Johnson CH. Circadian yin-yang regulation and its manipulation to globally reprogram gene expression.

Curr. Biol [print-electronic]

. 2013 Dec 12/2/2013; 23(23): 2365-74. PMID: 24210617, PMCID: PMC3889637, PII: S0960-9822(13)01251-7, DOI: 10.1016/j.cub.2013.10.011, ISSN: 1879-0445.

Xu Y, Weyman PD, Umetani M, Xiong J, Qin X, Xu Q, Iwasaki H, Johnson CH. Circadian yin-yang regulation and its manipulation to globally reprogram gene expression.

Curr. Biol [print-electronic]

. 2013 Dec 12/2/2013; 23(23): 2365-74. PMID: 24210617, PMCID: PMC3889637, PII: S0960-9822(13)01251-7, DOI: 10.1016/j.cub.2013.10.011, ISSN: 1879-0445.

de la Iglesia HO, Johnson CH. Biological clocks: riding the tides.

Curr. Biol

. 2013 Oct 10/21/2013; 23(20): R921-3. PMID: 24156810, PMCID: PMC4307598, PII: S0960-9822(13)01118-4, DOI: 10.1016/j.cub.2013.09.006, ISSN: 1879-0445.

Egli M, Johnson CH. A circadian clock nanomachine that runs without transcription or translation.

Curr. Opin. Neurobiol [print-electronic]

. 2013 Oct; 23(5): 732-40. PMID: 23571120, PMCID: PMC3735861, PII: S0959-4388(13)00060-3, DOI: 10.1016/j.conb.2013.02.012, ISSN: 1873-6882.

Bittman EL, Johnson CH. Animal care practices in research on biological rhythms and sleep [editorial].

J. Biol. Rhythms

. 2013 Oct; 28(5): 303-4. PMID: 24132055, PII: 28/5/303, DOI: 10.1177/0748730413502313, ISSN: 1552-4531.

Egli M, Johnson CH. A circadian clock nanomachine that runs without transcription or translation.

Curr. Opin. Neurobiol [print-electronic]

. 2013 Oct; 23(5): 732-40. PMID: 23571120, PMCID: PMC3735861, PII: S0959-4388(13)00060-3, DOI: 10.1016/j.conb.2013.02.012, ISSN: 1873-6882.

Ma P, Woelfle MA, Johnson CH. An Evolutionary Fitness Enhancement Conferred by the Circadian System in Cyanobacteria.

Chaos Solitons Fractals

. 2013 May 5/1/2013; 50: 65-74. PMID: 23626410, PMCID: PMC3633149, DOI: 10.1016/j.chaos.2012.11.006, ISSN: 0960-0779.

Ma P, Woelfle MA, Johnson CH. An Evolutionary Fitness Enhancement Conferred by the Circadian System in Cyanobacteria.

Chaos Solitons Fractals

. 2013 May 5/1/2013; 50: 65-74. PMID: 23626410, PMCID: PMC3633149, DOI: 10.1016/j.chaos.2012.11.006, ISSN: 0960-0779.

Xu Y, Ma P, Shah P, Rokas A, Liu Y, Johnson CH. Non-optimal codon usage is a mechanism to achieve circadian clock conditionality.

Nature [print-electronic]

. 2013 Mar 3/7/2013; 495(7439): 116-20. PMID: 23417065, PMCID: PMC3593822, PII: nature11942, DOI: 10.1038/nature11942, ISSN: 1476-4687.

Xu Y, Ma P, Shah P, Rokas A, Liu Y, Johnson CH. Non-optimal codon usage is a mechanism to achieve circadian clock conditionality.

Nature [print-electronic]

. 2013 Mar 3/7/2013; 495(7439): 116-20. PMID: 23417065, PMCID: PMC3593822, PII: nature11942, DOI: 10.1038/nature11942, ISSN: 1476-4687.

Shi SQ, Ansari TS, McGuinness OP, Wasserman DH, Johnson CH. Circadian disruption leads to insulin resistance and obesity.

Curr. Biol [print-electronic]

. 2013 Mar 3/4/2013; 23(5): 372-81. PMID: 23434278, PMCID: PMC3595381, PII: S0960-9822(13)00083-3, DOI: 10.1016/j.cub.2013.01.048, ISSN: 1879-0445.

Shi SQ, Ansari TS, McGuinness OP, Wasserman DH, Johnson CH. Circadian disruption leads to insulin resistance and obesity.

Curr. Biol [print-electronic]

. 2013 Mar 3/4/2013; 23(5): 372-81. PMID: 23434278, PMCID: PMC3595381, PII: S0960-9822(13)00083-3, DOI: 10.1016/j.cub.2013.01.048, ISSN: 1879-0445.

Egli M, Pattanayek R, Sheehan JH, Xu Y, Mori T, Smith JA, Johnson CH. Loop-loop interactions regulate KaiA-stimulated KaiC phosphorylation in the cyanobacterial KaiABC circadian clock.

Biochemistry [print-electronic]

. 2013 Feb 2/19/2013; 52(7): 1208-20. PMID: 23351065, PMCID: PMC3587310, DOI: 10.1021/bi301691a, ISSN: 1520-4995.

Egli M, Pattanayek R, Sheehan JH, Xu Y, Mori T, Smith JA, Johnson CH. Loop-loop interactions regulate KaiA-stimulated KaiC phosphorylation in the cyanobacterial KaiABC circadian clock.

Biochemistry [print-electronic]

. 2013 Feb 2/19/2013; 52(7): 1208-20. PMID: 23351065, PMCID: PMC3587310, DOI: 10.1021/bi301691a, ISSN: 1520-4995.

Gamble KL, Resuehr D, Johnson CH. Shift work and circadian dysregulation of reproduction.

Front Endocrinol (Lausanne)

. 2013; 4: 92. PMID: 23966978, PMCID: PMC3736045, DOI: 10.3389/fendo.2013.00092, ISSN: 1664-2392.

Edgar RS, Green EW, Zhao Y, van Ooijen G, Olmedo M, Qin X, Xu Y, Pan M, Valekunja UK, Feeney KA, Maywood ES, Hastings MH, Baliga NS, Merrow M, Millar AJ, Johnson CH, Kyriacou CP, O'Neill JS, Reddy AB. Peroxiredoxins are conserved markers of circadian rhythms.

Nature

. 2012 May 5/24/2012; 485(7399): 459-64. PMID: 22622569, PMCID: PMC3398137, PII: nature11088, DOI: 10.1038/nature11088, ISSN: 1476-4687.

Egli M, Mori T, Pattanayek R, Xu Y, Qin X, Johnson CH. Dephosphorylation of the core clock protein KaiC in the cyanobacterial KaiABC circadian oscillator proceeds via an ATP synthase mechanism.

Biochemistry [print-electronic]

. 2012 Feb 2/28/2012; 51(8): 1547-58. PMID: 22304631, PMCID: PMC3293397, DOI: 10.1021/bi201525n, ISSN: 1520-4995.

Egli M, Mori T, Pattanayek R, Xu Y, Qin X, Johnson CH. Dephosphorylation of the core clock protein KaiC in the cyanobacterial KaiABC circadian oscillator proceeds via an ATP synthase mechanism.

Biochemistry [print-electronic]

. 2012 Feb 2/28/2012; 51(8): 1547-58. PMID: 22304631, PMCID: PMC3293397, DOI: 10.1021/bi201525n, ISSN: 1520-4995.

Zhang Y, Xie Q, Robertson JB, Johnson CH. PHlash: a new genetically encoded and ratiometric luminescence sensor of intracellular pH.

PLoS ONE [print-electronic]

. 2012; 7(8): e43072. PMID: 22905204, PMCID: PMC3419163, PII: PONE-D-12-00656, DOI: 10.1371/journal.pone.0043072, ISSN: 1932-6203.

Zhang Y, Xie Q, Robertson JB, Johnson CH. PHlash: a new genetically encoded and ratiometric luminescence sensor of intracellular pH.

PLoS ONE [print-electronic]

. 2012; 7(8): e43072. PMID: 22905204, PMCID: PMC3419163, PII: PONE-D-12-00656, DOI: 10.1371/journal.pone.0043072, ISSN: 1932-6203.

Gamble KL, Motsinger-Reif AA, Hida A, Borsetti HM, Servick SV, Ciarleglio CM, Robbins S, Hicks J, Carver K, Hamilton N, Wells N, Summar ML, McMahon DG, Johnson CH. Shift work in nurses: contribution of phenotypes and genotypes to adaptation.

PLoS ONE

. 2011; 6(4): e18395. PMID: 21533241, PMCID: PMC3076422, DOI: 10.1371/journal.pone.0018395, ISSN: 1932-6203.

Robertson JB, Johnson CH. Luminescence as a continuous real-time reporter of promoter activity in yeast undergoing respiratory oscillations or cell division rhythms.

Methods Mol. Biol

. 2011; 734: 63-79. PMID: 21468985, PMCID: PMC3433746, DOI: 10.1007/978-1-61779-086-7_4, ISSN: 1940-6029.

Johnson CH, Stewart PL, Egli M. The cyanobacterial circadian system: from biophysics to bioevolution.

Annu Rev Biophys

. 2011; 40: 143-67. PMID: 21332358, PMCID: PMC3093959, DOI: 10.1146/annurev-biophys-042910-155317, ISSN: 1936-1238.

Xie Q, Soutto M, Xu X, Zhang Y, Johnson CH. Bioluminescence resonance energy transfer (BRET) imaging in plant seedlings and mammalian cells.

Methods Mol. Biol

. 2011; 680: 3-28. PMID: 21153370, PMCID: PMC3432581, DOI: 10.1007/978-1-60761-901-7_1, ISSN: 1940-6029.

Pattanayek R, Williams DR, Rossi G, Weigand S, Mori T, Johnson CH, Stewart PL, Egli M. Combined SAXS/EM based models of the S. elongatus post-translational circadian oscillator and its interactions with the output His-kinase SasA.

PLoS ONE [print-electronic]

. 2011; 6(8): e23697. PMID: 21887298, PMCID: PMC3161067, PII: PONE-D-11-10289, DOI: 10.1371/journal.pone.0023697, ISSN: 1932-6203.

Pattanayek R, Williams DR, Rossi G, Weigand S, Mori T, Johnson CH, Stewart PL, Egli M. Combined SAXS/EM based models of the S. elongatus post-translational circadian oscillator and its interactions with the output His-kinase SasA.

PLoS ONE [print-electronic]

. 2011; 6(8): e23697. PMID: 21887298, PMCID: PMC3161067, PII: PONE-D-11-10289, DOI: 10.1371/journal.pone.0023697, ISSN: 1932-6203.

Gamble KL, Motsinger-Reif AA, Hida A, Borsetti HM, Servick SV, Ciarleglio CM, Robbins S, Hicks J, Carver K, Hamilton N, Wells N, Summar ML, McMahon DG, Johnson CH. Shift work in nurses: contribution of phenotypes and genotypes to adaptation.

PLoS ONE

. 2011; 6(4): e18395. PMID: 21533241, PMCID: PMC3076422, DOI: 10.1371/journal.pone.0018395, ISSN: 1932-6203.

Robertson JB, Johnson CH. Luminescence as a continuous real-time reporter of promoter activity in yeast undergoing respiratory oscillations or cell division rhythms.

Methods Mol. Biol

. 2011; 734: 63-79. PMID: 21468985, PMCID: PMC3433746, DOI: 10.1007/978-1-61779-086-7_4, ISSN: 1940-6029.

Johnson CH, Stewart PL, Egli M. The cyanobacterial circadian system: from biophysics to bioevolution.

Annu Rev Biophys

. 2011; 40: 143-67. PMID: 21332358, PMCID: PMC3093959, DOI: 10.1146/annurev-biophys-042910-155317, ISSN: 1936-1238.

Xie Q, Soutto M, Xu X, Zhang Y, Johnson CH. Bioluminescence resonance energy transfer (BRET) imaging in plant seedlings and mammalian cells.

Methods Mol. Biol

. 2011; 680: 3-28. PMID: 21153370, PMCID: PMC3432581, DOI: 10.1007/978-1-60761-901-7_1, ISSN: 1940-6029.

Johnson CH. Circadian clocks and cell division: what's the pacemaker?.

Cell Cycle [print-electronic]

. 2010 Oct 10/1/2010; 9(19): 3864-73. PMID: 20890114, PMCID: PMC3047750, PII: 13205, ISSN: 1551-4005.

Johnson CH. Circadian clocks and cell division: what's the pacemaker?.

Cell Cycle [print-electronic]

. 2010 Oct 10/1/2010; 9(19): 3864-73. PMID: 20890114, PMCID: PMC3047750, PII: 13205, DOI: 10.4161/cc.9.19.13205, ISSN: 1551-4005.

Qin X, Byrne M, Mori T, Zou P, Williams DR, McHaourab H, Johnson CH. Intermolecular associations determine the dynamics of the circadian KaiABC oscillator.

Proc. Natl. Acad. Sci. U.S.A [print-electronic]

. 2010 Aug 8/17/2010; 107(33): 14805-10. PMID: 20679240, PMCID: PMC2930409, PII: 1002119107, DOI: 10.1073/pnas.1002119107, ISSN: 1091-6490.

Qin X, Byrne M, Mori T, Zou P, Williams DR, McHaourab H, Johnson CH. Intermolecular associations determine the dynamics of the circadian KaiABC oscillator.

Proc. Natl. Acad. Sci. U.S.A [print-electronic]

. 2010 Aug 8/17/2010; 107(33): 14805-10. PMID: 20679240, PMCID: PMC2930409, PII: 1002119107, DOI: 10.1073/pnas.1002119107, ISSN: 1091-6490.

Shi S, Hida A, McGuinness OP, Wasserman DH, Yamazaki S, Johnson CH. Circadian clock gene Bmal1 is not essential; functional replacement with its paralog, Bmal2.

Curr. Biol [print-electronic]

. 2010 Feb 2/23/2010; 20(4): 316-21. PMID: 20153195, PMCID: PMC2907674, PII: S0960-9822(09)02158-7, DOI: 10.1016/j.cub.2009.12.034, ISSN: 1879-0445.

Shi S, Hida A, McGuinness OP, Wasserman DH, Yamazaki S, Johnson CH. Circadian clock gene Bmal1 is not essential; functional replacement with its paralog, Bmal2.

Curr. Biol [print-electronic]

. 2010 Feb 2/23/2010; 20(4): 316-21. PMID: 20153195, PMCID: PMC2907674, PII: S0960-9822(09)02158-7, DOI: 10.1016/j.cub.2009.12.034, ISSN: 1879-0445.

Qin X, Byrne M, Xu Y, Mori T, Johnson CH. Coupling of a core post-translational pacemaker to a slave transcription/translation feedback loop in a circadian system.

PLoS Biol

. 2010; 8(6): e1000394. PMID: 20563306, PMCID: PMC2885980, DOI: 10.1371/journal.pbio.1000394, ISSN: 1545-7885.

Qin X, Byrne M, Xu Y, Mori T, Johnson CH. Coupling of a core post-translational pacemaker to a slave transcription/translation feedback loop in a circadian system.

PLoS Biol

. 2010; 8(6): e1000394. PMID: 20563306, PMCID: PMC2885980, DOI: 10.1371/journal.pbio.1000394, ISSN: 1545-7885.

Xu X, Graeff R, Xie Q, Gamble KL, Mori T, Johnson CH. Comment on "The Arabidopsis circadian clock incorporates a cADPR-based feedback loop".

Science

. 2009 Oct 10/9/2009; 326(5950): 230; author reply 230. PMID: 19815758, PMCID: PMC2934760, PII: 326/5950/230-b, DOI: 10.1126/science.1169503, ISSN: 1095-9203.

Robertson JB, Zhang Y, Johnson CH. Light-emitting diode flashlights as effective and inexpensive light sources for fluorescence microscopy.

J Microsc

. 2009 Oct; 236(1): 1-4. PMID: 19772530, PMCID: PMC2751867, PII: JMI3208, DOI: 10.1111/j.1365-2818.2009.03208.x, ISSN: 1365-2818.

Pattanayek R, Mori T, Xu Y, Pattanayek S, Johnson CH, Egli M. Structures of KaiC circadian clock mutant proteins: a new phosphorylation site at T426 and mechanisms of kinase, ATPase and phosphatase.

PLoS ONE

. 2009; 4(11): e7529. PMID: 19956664, PMCID: PMC2777353, DOI: 10.1371/journal.pone.0007529, ISSN: 1932-6203.

Xu Y, Mori T, Qin X, Yan H, Egli M, Johnson CH. Intramolecular regulation of phosphorylation status of the circadian clock protein KaiC.

PLoS ONE

. 2009; 4(11): e7509. PMID: 19946629, PMCID: PMC2778140, DOI: 10.1371/journal.pone.0007509, ISSN: 1932-6203.

J.L. Ditty, S.R. Mackey, C.H. Johnson, editors.

Bacterial Circadian Programs

. [place unknown: publisher unknown]; 2009.

Pattanayek R, Mori T, Xu Y, Pattanayek S, Johnson CH, Egli M. Structures of KaiC circadian clock mutant proteins: a new phosphorylation site at T426 and mechanisms of kinase, ATPase and phosphatase.

PLoS ONE

. 2009; 4(11): e7529. PMID: 19956664, PMCID: PMC2777353, DOI: 10.1371/journal.pone.0007529, ISSN: 1932-6203.

Robertson JB, Stowers CC, Boczko E, Johnson CH. Real-time luminescence monitoring of cell-cycle and respiratory oscillations in yeast.

Proc. Natl. Acad. Sci. U.S.A [print-electronic]

. 2008 Nov 11/18/2008; 105(46): 17988-93. PMID: 19004762, PMCID: PMC2584751, PII: 0809482105, DOI: 10.1073/pnas.0809482105, ISSN: 1091-6490.

Johnson CH, Egli M, Stewart PL. Structural insights into a circadian oscillator.

Science

. 2008 Oct 10/31/2008; 322(5902): 697-701. PMID: 18974343, PMCID: PMC2588432, PII: 322/5902/697, DOI: 10.1126/science.1150451, ISSN: 1095-9203.

Vougogiannopoulou K, Ferandin Y, Bettayeb K, Myrianthopoulos V, Lozach O, Fan Y, Johnson CH, Magiatis P, Skaltsounis AL, Mikros E, Meijer L. Soluble 3',6-substituted indirubins with enhanced selectivity toward glycogen synthase kinase -3 alter circadian period.

J. Med. Chem [print-electronic]

. 2008 Oct 10/23/2008; 51(20): 6421-31. PMID: 18816110, PMCID: PMC2717725, DOI: 10.1021/jm800648y, ISSN: 1520-4804.

Johnson CH, Mori T, Xu Y. A cyanobacterial circadian clockwork.

Curr. Biol

. 2008 Sep 9/9/2008; 18(17): R816-R825. PMID: 18786387, PMCID: PMC2585598, PII: S0960-9822(08)00877-4, DOI: 10.1016/j.cub.2008.07.012, ISSN: 0960-9822.

Ciarleglio CM, Ryckman KK, Servick SV, Hida A, Robbins S, Wells N, Hicks J, Larson SA, Wiedermann JP, Carver K, Hamilton N, Kidd KK, Kidd JR, Smith JR, Friedlaender J, McMahon DG, Williams SM, Summar ML, Johnson CH. Genetic differences in human circadian clock genes among worldwide populations.

J. Biol. Rhythms

. 2008 Aug; 23(4): 330-40. PMID: 18663240, PMCID: PMC2579796, PII: 23/4/330, DOI: 10.1177/0748730408320284, ISSN: 0748-7304.

Pattanayek R, Williams DR, Pattanayek S, Mori T, Johnson CH, Stewart PL, Egli M. Structural model of the circadian clock KaiB-KaiC complex and mechanism for modulation of KaiC phosphorylation.

EMBO J [print-electronic]

. 2008 Jun 6/18/2008; 27(12): 1767-78. PMID: 18497745, PMCID: PMC2435126, PII: emboj2008104, DOI: 10.1038/emboj.2008.104, ISSN: 1460-2075.

Bonneau R, Facciotti MT, Reiss DJ, Schmid AK, Pan M, Kaur A, Thorsson V, Shannon P, Johnson MH, Bare JC, Longabaugh W, Vuthoori M, Whitehead K, Madar A, Suzuki L, Mori T, Chang DE, Diruggiero J, Johnson CH, Hood L, Baliga NS. A predictive model for transcriptional control of physiology in a free living cell.

Cell

. 2007 Dec 12/28/2007; 131(7): 1354-65. PMID: 18160043, PII: S0092-8674(07)01416-X, DOI: 10.1016/j.cell.2007.10.053, ISSN: 0092-8674.

Woelfle MA, Xu Y, Qin X, Johnson CH. Circadian rhythms of superhelical status of DNA in cyanobacteria.

Proc. Natl. Acad. Sci. U.S.A [print-electronic]

. 2007 Nov 11/20/2007; 104(47): 18819-24. PMID: 18000054, PMCID: PMC2141860, PII: 0706069104, DOI: 10.1073/pnas.0706069104, ISSN: 1091-6490.

Xu X, Hotta CT, Dodd AN, Love J, Sharrock R, Lee YW, Xie Q, Johnson CH, Webb AA. Distinct light and clock modulation of cytosolic free Ca2+ oscillations and rhythmic CHLOROPHYLL A/B BINDING PROTEIN2 promoter activity in Arabidopsis.

Plant Cell [print-electronic]

. 2007 Nov; 19(11): 3474-90. PMID: 17982000, PMCID: PMC2174886, PII: tpc.106.046011, DOI: 10.1105/tpc.106.046011, ISSN: 1040-4651.

Fan Y, Hida A, Anderson DA, Izumo M, Johnson CH. Cycling of CRYPTOCHROME proteins is not necessary for circadian-clock function in mammalian fibroblasts.

Curr. Biol [print-electronic]

. 2007 Jul 7/3/2007; 17(13): 1091-100. PMID: 17583506, PMCID: PMC3434691, PII: S0960-9822(07)01472-8, DOI: 10.1016/j.cub.2007.05.048, ISSN: 0960-9822.

Xu X, Soutto M, Xie Q, Servick S, Subramanian C, von Arnim AG, Johnson CH. Imaging protein interactions with bioluminescence resonance energy transfer (BRET) in plant and mammalian cells and tissues.

Proc. Natl. Acad. Sci. U.S.A [print-electronic]

. 2007 Jun 6/12/2007; 104(24): 10264-9. PMID: 17551013, PMCID: PMC1891211, PII: 0701987104, DOI: 10.1073/pnas.0701987104, ISSN: 0027-8424.

Mori T, Williams DR, Byrne MO, Qin X, Egli M, Mchaourab HS, Stewart PL, Johnson CH. Elucidating the ticking of an in vitro circadian clockwork.

PLoS Biol

. 2007 Apr; 5(4): e93. PMID: 17388688, PMCID: PMC1831719, PII: 06-PLBI-RA-2188R2, DOI: 10.1371/journal.pbio.0050093, ISSN: 1545-7885.

Johnson CH. Bacterial circadian programs.

Cold Spring Harb. Symp. Quant. Biol

. 2007; 72: 395-404. PMID: 18419297, DOI: 10.1101/sqb.2007.72.027, ISSN: 0091-7451.

Woelfle MA, Johnson CH. No promoter left behind: global circadian gene expression in cyanobacteria.

J. Biol. Rhythms

. 2006 Dec; 21(6): 419-31. PMID: 17107933, PMCID: PMC3431602, PII: 21/6/419, DOI: 10.1177/0748730406294418, ISSN: 0748-7304.

Izumo M, Sato TR, Straume M, Johnson CH. Quantitative analyses of circadian gene expression in mammalian cell cultures.

PLoS Comput. Biol

. 2006 Oct; 2(10): e136. PMID: 17040123, PMCID: PMC1599765, PII: 06-PLCB-RA-0163R2, DOI: 10.1371/journal.pcbi.0020136, ISSN: 1553-7358.

Subramanian C, Woo J, Cai X, Xu X, Servick S, Johnson CH, Nebenführ A, von Arnim AG. A suite of tools and application notes for in vivo protein interaction assays using bioluminescence resonance energy transfer (BRET).

Plant J [print-electronic]

. 2006 Oct; 48(1): 138-52. PMID: 16925598, PII: TPJ2851, DOI: 10.1111/j.1365-313X.2006.02851.x, ISSN: 0960-7412.

Pattanayek R, Williams DR, Pattanayek S, Xu Y, Mori T, Johnson CH, Stewart PL, Egli M. Analysis of KaiA-KaiC protein interactions in the cyano-bacterial circadian clock using hybrid structural methods.

EMBO J [print-electronic]

. 2006 May 5/3/2006; 25(9): 2017-28. PMID: 16628225, PMCID: PMC1456936, PII: 7601086, DOI: 10.1038/sj.emboj.7601086, ISSN: 0261-4189.

Johnson, C.H., and S.S. Golden. Circadian Rhythms in Cyanobacteria.

In: Nature Encyclopedia of Life Sciences, Nature Publishing Group, London: www.els.net

. 2006.

Johnson, C.H.. Reminiscences from Pittendrigh's last Ph.D. student.

Resonance

. 2006; 11: 22-31.

Johnson, C.H., R. Shingles, and W.F. Ettinger.

In: The Structure and Function of Plastids, Chapter 20

. [place unknown: publisher unknown]; 2006. (23).

Mittag M, Kiaulehn S, Johnson CH. The circadian clock in Chlamydomonas reinhardtii. What is it for? What is it similar to?.

Plant Physiol

. 2005 Feb; 137(2): 399-409. PMID: 15710681, PMCID: PMC1065344, PII: 137/2/399, DOI: 10.1104/pp.104.052415, ISSN: 0032-0889.

Johnson CH. Testing the adaptive value of circadian systems.

Meth. Enzymol

. 2005; 393: 818-37. PMID: 15817326, PII: S0076687905930437, DOI: 10.1016/S0076-6879(05)93043-7, ISSN: 1557-7988.

Johnson, C.H. Testing the adaptive value of circadian systems.

Methods in Enzymology

. 2005; 393: 818-37.

Soutto M., Y. Xu, and C. H. Johnson. Bioluminescence RET (BRET): techniques and potential.

In: Molecular Imaging: FRET Microscopy and Spectroscopy

. 2005; 260-71.

Johnson, C.H. and C.P. Kyriacou.

In: Endogenous Plant Rhythms

. [place unknown: publisher unknown]; 2005.

Xu Y, Mori T, Pattanayek R, Pattanayek S, Egli M, Johnson CH. Identification of key phosphorylation sites in the circadian clock protein KaiC by crystallographic and mutagenetic analyses.

Proc. Natl. Acad. Sci. U.S.A [print-electronic]

. 2004 Sep 9/21/2004; 101(38): 13933-8. PMID: 15347809, PMCID: PMC518856, PII: 0404768101, DOI: 10.1073/pnas.0404768101, ISSN: 0027-8424.

Woelfle MA, Ouyang Y, Phanvijhitsiri K, Johnson CH. The adaptive value of circadian clocks: an experimental assessment in cyanobacteria.

Curr. Biol

. 2004 Aug 8/24/2004; 14(16): 1481-6. PMID: 15324665, PII: S0960982204006062, DOI: 10.1016/j.cub.2004.08.023, ISSN: 0960-9822.

Pattanayek R, Wang J, Mori T, Xu Y, Johnson CH, Egli M. Visualizing a circadian clock protein: crystal structure of KaiC and functional insights.

Mol. Cell

. 2004 Aug 8/13/2004; 15(3): 375-88. PMID: 15304218, PII: S1097276504004356, DOI: 10.1016/j.molcel.2004.07.013, ISSN: 1097-2765.

Johnson CH. Precise circadian clocks in prokaryotic cyanobacteria.

Curr Issues Mol Biol

. 2004 Jul; 6(2): 103-10. PMID: 15119821, ISSN: 1467-3037.

Subramanian C, Kim BH, Lyssenko NN, Xu X, Johnson CH, von Arnim AG. The Arabidopsis repressor of light signaling, COP1, is regulated by nuclear exclusion: mutational analysis by bioluminescence resonance energy transfer.

Proc. Natl. Acad. Sci. U.S.A [print-electronic]

. 2004 Apr 4/27/2004; 101(17): 6798-802. PMID: 15084749, PMCID: PMC404125, PII: 0307964101, DOI: 10.1073/pnas.0307964101, ISSN: 0027-8424.

Min H, Liu Y, Johnson CH, Golden SS. Phase determination of circadian gene expression in Synechococcus elongatus PCC 7942.

J. Biol. Rhythms

. 2004 Apr; 19(2): 103-12. PMID: 15038850, DOI: 10.1177/0748730403262056, ISSN: 0748-7304.

Johnson CH. Global orchestration of gene expression by the biological clock of cyanobacteria.

Genome Biol [print-electronic]

. 2004; 5(4): 217. PMID: 15059250, PMCID: PMC395776, PII: gb-2004-5-4-217, DOI: 10.1186/gb-2004-5-4-217, ISSN: 1474-760X.

Subramanian C, Xu Y, Johnson CH, von Arnim AG. In vivo detection of protein-protein interaction in plant cells using BRET.

Methods Mol. Biol

. 2004; 284: 271-86. PMID: 15173623, PII: 1-59259-816-1:271, DOI: 10.1385/1-59259-816-1:271, ISSN: 1064-3745.

Johnson, C.H. and M. Egli. Visualizing a biological clockwork's cogs.

Nature Structural and Molecular Biology

. 2004; 11((7)): 584-5.

Johnson, C.H.. As time glows by in bacteria.

Nature

. 2004; 430((1)): 23-4.

Izumo M, Johnson CH, Yamazaki S. Circadian gene expression in mammalian fibroblasts revealed by real-time luminescence reporting: temperature compensation and damping.

Proc. Natl. Acad. Sci. U.S.A [print-electronic]

. 2003 Dec 12/23/2003; 100(26): 16089-94. PMID: 14657355, PMCID: PMC307697, PII: 2536313100, DOI: 10.1073/pnas.2536313100, ISSN: 0027-8424.

Johnson CH, Elliott JA, Foster R. Entrainment of circadian programs.

Chronobiol. Int

. 2003 Sep; 20(5): 741-74. PMID: 14535352, ISSN: 0742-0528.

Schoenhard JA, Smith LH, Painter CA, Eren M, Johnson CH, Vaughan DE. Regulation of the PAI-1 promoter by circadian clock components: differential activation by BMAL1 and BMAL2.

J. Mol. Cell. Cardiol

. 2003 May; 35(5): 473-81. PMID: 12738229, PII: S0022282803000518, ISSN: 0022-2828.

Xu Y, Mori T, Johnson CH. Cyanobacterial circadian clockwork: roles of KaiA, KaiB and the kaiBC promoter in regulating KaiC.

EMBO J

. 2003 May 5/1/2003; 22(9): 2117-26. PMID: 12727878, PMCID: PMC156062, DOI: 10.1093/emboj/cdg168, ISSN: 0261-4189.

Xu Y, Kanauchi A, von Arnim AG, Piston DW, Johnson CH. Bioluminescence resonance energy transfer: monitoring protein-protein interactions in living cells.

Meth. Enzymol

. 2003; 360: 289-301. PMID: 12622156, ISSN: 0076-6879.

Hastings JW, Johnson CH. Bioluminescence and chemiluminescence.

Meth. Enzymol

. 2003; 360: 75-104. PMID: 12622147, ISSN: 0076-6879.

Mori T, Saveliev SV, Xu Y, Stafford WF, Cox MM, Inman RB, Johnson CH. Circadian clock protein KaiC forms ATP-dependent hexameric rings and binds DNA.

Proc. Natl. Acad. Sci. U.S.A [print-electronic]

. 2002 Dec 12/24/2002; 99(26): 17203-8. PMID: 12477935, PMCID: PMC139293, PII: 262578499, DOI: 10.1073/pnas.262578499, ISSN: 0027-8424.

Schoenhard JA, Eren M, Johnson CH, Vaughan DE. Alternative splicing yields novel BMAL2 variants: tissue distribution and functional characterization.

Am. J. Physiol., Cell Physiol

. 2002 Jul; 283(1): C103-14. PMID: 12055078, DOI: 10.1152/ajpcell.00541.2001, ISSN: 0363-6143.

Sai J, Johnson CH. Dark-stimulated calcium ion fluxes in the chloroplast stroma and cytosol.

Plant Cell

. 2002 Jun; 14(6): 1279-91. PMID: 12084827, PMCID: PMC150780, ISSN: 1040-4651.

Suzuki L, Johnson CH. Photoperiodic control of germination in the unicell Chlamydomonas.

Naturwissenschaften

. 2002 May; 89(5): 214-20. PMID: 12135086, ISSN: 0028-1042.

Xu Y, Johnson CH, Piston D. Bioluminescence resonance energy transfer assays for protein-protein interactions in living cells.

Methods Mol. Biol

. 2002; 183: 121-33. PMID: 12136748, PII: 1-59259-280-5-121, DOI: 10.1385/1-59259-280-5:121, ISSN: 1064-3745.

Mori T, Johnson CH. Circadian programming in cyanobacteria.

Semin. Cell Dev. Biol

. 2001 Aug; 12(4): 271-8. PMID: 11463211, PII: S1084-9521(01)90254-X, DOI: 10.1006/scdb.2001.0254, ISSN: 1084-9521.

Xu Y, Johnson CH. A clock- and light-regulated gene that links the circadian oscillator to LHCB gene expression.

Plant Cell

. 2001 Jun; 13(6): 1411-25. PMID: 11402169, PMCID: PMC135572, ISSN: 1040-4651.

Mori T, Johnson CH. Independence of circadian timing from cell division in cyanobacteria.

J. Bacteriol

. 2001 Apr; 183(8): 2439-44. PMID: 11274102, PMCID: PMC95159, DOI: 10.1128/JB.183.8.2439-2444.2001, ISSN: 0021-9193.

Johnson CH. Endogenous timekeepers in photosynthetic organisms.

Annu. Rev. Physiol

. 2001; 63: 695-728. PMID: 11181973, PII: 63/1/695, DOI: 10.1146/annurev.physiol.63.1.695, ISSN: 0066-4278.

Dassarma S, Kennedy SP, Berquist B, Victor Ng W, Baliga NS, Spudich JL, Krebs MP, Eisen JA, Johnson CH, Hood L. Genomic perspective on the photobiology of Halobacterium species NRC-1, a phototrophic, phototactic, and UV-tolerant haloarchaeon.

Photosyn. Res

. 2001; 70(1): 3-17. PMID: 16228359, DOI: 10.1023/A:1013879706863, ISSN: 1573-5079.

Xu Y, Mori T, Johnson CH. Circadian clock-protein expression in cyanobacteria: rhythms and phase setting.

EMBO J

. 2000 Jul 7/3/2000; 19(13): 3349-57. PMID: 10880447, PMCID: PMC313937, DOI: 10.1093/emboj/19.13.3349, ISSN: 0261-4189.

Nikaido SS, Johnson CH. Daily and circadian variation in survival from ultraviolet radiation in Chlamydomonas reinhardtii.

Photochem. Photobiol

. 2000 Jun; 71(6): 758-65. PMID: 10857373, ISSN: 0031-8655.

Mori T, Johnson CH. Circadian control of cell division in unicellular organisms.

Prog Cell Cycle Res

. 2000; 4: 185-92. PMID: 10740825, ISSN: 1087-2957.

Johnson CH. Forty years of PRCs--what have we learned?.

Chronobiol. Int

. 1999 Nov; 16(6): 711-43. PMID: 10584173, ISSN: 0742-0528.

Sai J, Johnson CH. Different circadian oscillators control Ca(2+) fluxes and lhcb gene expression.

Proc. Natl. Acad. Sci. U.S.A

. 1999 Sep 9/28/1999; 96(20): 11659-63. PMID: 10500233, PMCID: PMC18090, ISSN: 0027-8424.

Xu Y, Piston DW, Johnson CH. A bioluminescence resonance energy transfer (BRET) system: application to interacting circadian clock proteins.

Proc. Natl. Acad. Sci. U.S.A

. 1999 Jan 1/5/1999; 96(1): 151-6. PMID: 9874787, PMCID: PMC15108, ISSN: 0027-8424.

Johnson CH, Golden SS. Circadian programs in cyanobacteria: adaptiveness and mechanism.

Annu. Rev. Microbiol

. 1999; 53: 389-409. PMID: 10547696, DOI: 10.1146/annurev.micro.53.1.389, ISSN: 0066-4227.

Golden SS, Johnson CH, Kondo T. The cyanobacterial circadian system: a clock apart.

Curr. Opin. Microbiol

. 1998 Dec; 1(6): 669-73. PMID: 10066545, PII: S1369-5274(98)80113-6, ISSN: 1369-5274.

Johnson CH, Golden SS, Kondo T. Adaptive significance of circadian programs in cyanobacteria.

Trends Microbiol

. 1998 Oct; 6(10): 407-10. PMID: 9807785, PII: S0966-842X(98)01356-0, ISSN: 0966-842X.

Ishiura M, Kutsuna S, Aoki S, Iwasaki H, Andersson CR, Tanabe A, Golden SS, Johnson CH, Kondo T. Expression of a gene cluster kaiABC as a circadian feedback process in cyanobacteria.

Science

. 1998 Sep 9/4/1998; 281(5382): 1519-23. PMID: 9727980, ISSN: 0036-8075.

Ouyang Y, Andersson CR, Kondo T, Golden SS, Johnson CH. Resonating circadian clocks enhance fitness in cyanobacteria.

Proc. Natl. Acad. Sci. U.S.A

. 1998 Jul 7/21/1998; 95(15): 8660-4. PMID: 9671734, PMCID: PMC21132, ISSN: 0027-8424.

Golden SS, Ishiura M, Johnson CH, Kondo T. CYANOBACTERIAL CIRCADIAN RHYTHMS.

Annu. Rev. Plant Physiol. Plant Mol. Biol

. 1997 Jun; 48: 327-54. PMID: 15012266, DOI: 10.1146/annurev.arplant.48.1.327, ISSN: 1040-2519.

Mori T, Binder B, Johnson CH. Circadian gating of cell division in cyanobacteria growing with average doubling times of less than 24 hours.

Proc. Natl. Acad. Sci. U.S.A

. 1996 Sep 9/17/1996; 93(19): 10183-8. PMID: 8816773, PMCID: PMC38358, ISSN: 0027-8424.

Jacobshagen S, Kindle KL, Johnson CH. Transcription of CABII is regulated by the biological clock in Chlamydomonas reinhardtii.

Plant Mol. Biol

. 1996 Sep; 31(6): 1173-84. PMID: 8914533, ISSN: 0167-4412.

Johnson CH, Golden SS, Ishiura M, Kondo T. Circadian clocks in prokaryotes.

Mol. Microbiol

. 1996 Jul; 21(1): 5-11. PMID: 8843429, ISSN: 0950-382X.

Liu Y, Tsinoremas NF, Golden SS, Kondo T, Johnson CH. Circadian expression of genes involved in the purine biosynthetic pathway of the cyanobacterium Synechococcus sp. strain PCC 7942.

Mol. Microbiol

. 1996 Jun; 20(5): 1071-81. PMID: 8809759, ISSN: 0950-382X.

Tsinoremas NF, Ishiura M, Kondo T, Andersson CR, Tanaka K, Takahashi H, Johnson CH, Golden SS. A sigma factor that modifies the circadian expression of a subset of genes in cyanobacteria.

EMBO J

. 1996 May 5/15/1996; 15(10): 2488-95. PMID: 8665856, PMCID: PMC450181, ISSN: 0261-4189.

Johnson CH, Knight MR, Kondo T, Masson P, Sedbrook J, Haley A, Trewavas A. Circadian oscillations of cytosolic and chloroplastic free calcium in plants.

Science

. 1995 Sep 9/29/1995; 269(5232): 1863-5. PMID: 7569925, ISSN: 0036-8075.

Liu Y, Tsinoremas NF, Johnson CH, Lebedeva NV, Golden SS, Ishiura M, Kondo T. Circadian orchestration of gene expression in cyanobacteria.

Genes Dev

. 1995 Jun 6/15/1995; 9(12): 1469-78. PMID: 7601351, ISSN: 0890-9369.

Goto K, Johnson CH. Is the cell division cycle gated by a circadian clock? The case of Chlamydomonas reinhardtii.

J. Cell Biol

. 1995 May; 129(4): 1061-9. PMID: 7744955, PMCID: PMC2120501, ISSN: 0021-9525.

Liu Y, Golden SS, Kondo T, Ishiura M, Johnson CH. Bacterial luciferase as a reporter of circadian gene expression in cyanobacteria.

J. Bacteriol

. 1995 Apr; 177(8): 2080-6. PMID: 7536731, PMCID: PMC176852, ISSN: 0021-9193.

Johnson CH, Nakaoka Y, Miwa I. The effects of altering extracellular potassium ion concentration on the membrane potential and circadian clock of Paramecium bursaria.

J. Exp. Biol

. 1994 Dec; 197: 295-308. PMID: 7852906, ISSN: 0022-0949.

Kondo T, Tsinoremas NF, Golden SS, Johnson CH, Kutsuna S, Ishiura M. Circadian clock mutants of cyanobacteria.

Science

. 1994 Nov 11/18/1994; 266(5188): 1233-6. PMID: 7973706, ISSN: 0036-8075.

Johnson CH. Illuminating the clock: circadian photobiology.

Semin. Cell Biol

. 1994 Oct; 5(5): 355-62. PMID: 7881075, ISSN: 1043-4682.

Jacobshagen S, Johnson CH. Circadian rhythms of gene expression in Chlamydomonas reinhardtii: circadian cycling of mRNA abundances of cab II, and possibly of beta-tubulin and cytochrome c.

Eur. J. Cell Biol

. 1994 Jun; 64(1): 142-52. PMID: 7957302, ISSN: 0171-9335.

Kondo T, Strayer CA, Kulkarni RD, Taylor W, Ishiura M, Golden SS, Johnson CH. Circadian rhythms in prokaryotes: luciferase as a reporter of circadian gene expression in cyanobacteria.

Proc. Natl. Acad. Sci. U.S.A

. 1993 Jun 6/15/1993; 90(12): 5672-6. PMID: 8516317, PMCID: PMC46783, ISSN: 0027-8424.

Johnson CH, Kondo T. Light pulses induce "singular" behavior and shorten the period of the circadian phototaxis rhythm in the CW15 strain of Chlamydomonas.

J. Biol. Rhythms

. 1992; 7(4): 313-27. PMID: 1286203, ISSN: 0748-7304.

Johnson CH, Kondo T, Hastings JW. Action Spectrum for Resetting the Circadian Phototaxis Rhythm in the CW15 Strain of Chlamydomonas: II. Illuminated Cells.

Plant Physiol

. 1991 Nov; 97(3): 1122-9. PMID: 16668498, PMCID: PMC1081131, ISSN: 0032-0889.

Kondo T, Johnson CH, Hastings JW. Action Spectrum for Resetting the Circadian Phototaxis Rhythm in the CW15 Strain of Chlamydomonas: I. Cells in Darkness.

Plant Physiol

. 1991 Jan; 95(1): 197-205. PMID: 16667951, PMCID: PMC1077506, ISSN: 0032-0889.

Johnson CH, Nakashima H. Cycloheximide inhibits light-induced phase shifting of the circadian clock in Neurospora.

J. Biol. Rhythms

. 1990; 5(2): 159-67. PMID: 2133125, ISSN: 0748-7304.

Johnson CH, Hastings JW. Circadian phototransduction: phase resetting and frequency of the circadian clock of Gonyaulax cells in red light.

J. Biol. Rhythms

. 1989; 4(4): 417-37. PMID: 2519604, ISSN: 0748-7304.

Johnson CH, Miwa I, Kondo T, Hastings JW. Circadian rhythm of photoaccumulation in Paramecium bursaria.

J. Biol. Rhythms

. 1989; 4(4): 405-15. PMID: 2519603, ISSN: 0748-7304.

Broda H, Johnson CH, Taylor WR, Hastings JW. Temperature dependence of phase response curves for drug-induced phase shifts.

J. Biol. Rhythms

. 1989; 4(3): 327-33. PMID: 2519597, ISSN: 0748-7304.

Nicolas MT, Nicolas G, Johnson CH, Bassot JM, Hastings JW. Characterization of the bioluminescent organelles in Gonyaulax polyedra (dinoflagellates) after fast-freeze fixation and antiluciferase immunogold staining.

J. Cell Biol

. 1987 Aug; 105(2): 723-35. PMID: 2442172, PMCID: PMC2114768, ISSN: 0021-9525.

Olesiak W, Ungar A, Johnson CH, Hastings JW. Are protein synthesis inhibition and phase shifting of the circadian clock in Gonyaulax correlated?.

J. Biol. Rhythms

. 1987; 2(2): 121-38. PMID: 2979654, ISSN: 0748-7304.

Nicolas MT, Johnson CH, Bassot JM, Hastings JW. Immunogold labeling of organelles in the bioluminescent dinoflagellate Gonyaulax polyedra with anti-luciferase antibody.

Cell Biol. Int. Rep

. 1985 Sep; 9(9): 797-802. PMID: 3899376, ISSN: 0309-1651.

Johnson CH, Inoué S, Flint A, Hastings JW. Compartmentalization of algal bioluminescence: autofluorescence of bioluminescent particles in the dinoflagellate Gonyaulax as studied with image-intensified video microscopy and flow cytometry.

J. Cell Biol

. 1985 May; 100(5): 1435-46. PMID: 4039325, PMCID: PMC2113859, ISSN: 0021-9525.

Vanderbilt University School of Medicine (2025)
Top Articles
Latest Posts
Recommended Articles
Article information

Author: Sen. Ignacio Ratke

Last Updated:

Views: 6231

Rating: 4.6 / 5 (56 voted)

Reviews: 87% of readers found this page helpful

Author information

Name: Sen. Ignacio Ratke

Birthday: 1999-05-27

Address: Apt. 171 8116 Bailey Via, Roberthaven, GA 58289

Phone: +2585395768220

Job: Lead Liaison

Hobby: Lockpicking, LARPing, Lego building, Lapidary, Macrame, Book restoration, Bodybuilding

Introduction: My name is Sen. Ignacio Ratke, I am a adventurous, zealous, outstanding, agreeable, precious, excited, gifted person who loves writing and wants to share my knowledge and understanding with you.